Origami DNA as components of nanoparticle synthesis in Nano bio Robots based on Nano-Microelectronics PhD (Educational-Research PhD)

Researcher  and author: Dr.   (   Afshin Rashid)

Note: DNA Origami  is one of the newest techniques of using DNA as building blocks in the synthesis of nano-robots Biologic nanoparticles (Nano bio Robot s) is . This is one of the newest methods in the field of nanoelectronics technology, which has its own limitations and opportunities. "Origami" is a Japanese word that means folding a simple sheet to a desired shape and with a special dimension.

Although DNA is the natural choice for building the active structures of nanobots, DNA is origami  . Not for nanorobotic applications, but due to the lack of structural and catalytic diversity, there is also the possibility of molecular walkers on origami and switches. Nano robots made from DNA origami  DNA origami  capacity computing to showcase the work of pre-programmed within the living organism. In the structure of  nano-robots they have created DNA, a DNA pipes open a It has a hinge side and can be closed. The drug-laden DNA tube is closed by a DNA aptamer  and configured  to identify and search for disease-related proteins. When the nano-robot origami  DNA origami They hit infected cells, the aptamers separate, and release the drug.


DNA origami  has a completely different approach to multi-strand design. Usually the genomic DNA of a circular single-stranded nucleotide Nano Bots (Nano bio Robot as a scaffold used and hundreds of short auxiliary called the punch for the latest Scaffolding longer specific structure is used. In the process of folding, DNA scaffolds Acts as a guide or a seed, which increases the folding efficiency and resistance to the stoichiometry of the filaments in the  Nano bio Robot  .


Conclusion: 

DNA origami  is one of the newest techniques of using DNA as building blocks in the synthesis of nano-robots Biologic nanoparticles (Nano bio Robot s) is . This is one of the newest methods in the field of nanoelectronics technology, which has its own limitations and opportunities. "Origami" is a Japanese word that means folding a simple sheet to a desired shape and with a special dimension.

Author: Dr.  ( Afshin Rashid)

PhD student in nano-microelectronics at Islamic Azad University, Science and Research Branch, Tehran