_ Section of the simulation process in (electrical nanoparticles)

Investigating the performance of floating particles in the process of simulating plasmon-enhanced nanosensors based on multi- to single-layer nanoparticles 

Researcher  and author:  Dr. (   Afshin Rashid)

Note:  Plasmonic-based nanosensors have received considerable attention due to their extreme sensitivity even at the single molecule level.  However, at present, plasmonic-enhanced nanosensors have not achieved excellent performances in practical applications, and their detection at femtomolar or atmolar concentrations is very challenging.

Large-sized floating particles with a slippery surface may prevent the coffee ring effect and enhance the ability to localize the analyte in plasmonic sensitive sites through aggregation and lifting effect.  The current floating particle strategy can be used in a wide variety of plasmonic-enhanced sensing applications for cost-effective, simple, fast, flexible, and portable detection. For nanosensors,  a plasmonic nano-sensitization process involving complex interaction There are three elements among photons, molecules and nanostructures .  , nanorods, nanotubes and nanoparticles, to increase advanced surface Raman spectroscopy and fluorescence sensitivity in  plasmonic-enhanced nanosensors based on multi- to single-layer nanoparticles and detection for many small sections or molecules. Weak absorption is difficult in plasmonic nanosensors. The performance of floating particles for plasmon-enhanced nanosensors based on multi- to monolayer nanoparticles in the interaction between molecules and nanostructure surfaces.  Based on a pathway for colloidal aggregation  , weakly adsorbed molecules cannot be adsorbed on a metal surface during rapid aggregation.  Therefore, this natural defect makes these nanosensors not show significant sensitivity.  On a solid surface with precise nanoparticles,  immersing the substrate of the nanosensor in the solution containing the analyte may result in homogeneous molecule absorption.  However, the absorption time (eg, several hours) is far beyond practical time frames.  Instead, by drying the droplet containing the analyte on a substrate, the distribution of the molecule on the plasmon-enhanced nanosensors based on multi- to monolayer nanoparticles may face the problem of uniformity.

 

Localization of analytes towards plasmonic hot spots with high efficiency is of great importance in increasing the sensitivity of plasmonic nanosensors. The coffee ring effect is a very common phenomenon, and its essence is that the capillary flow outward from the center of the droplet transfers the scattered droplets to the edge, which   continues  with evaporation .  In many detections based on plasmonic nanosensors, the formation of a loop may lead to a completely uncontrolled distribution of colloidal nanoparticles and target molecules, resulting in declining signal uniformity and lower sensitivity in  floating particle performance for nanosensors. ) plasmonic amplification based on nanoparticles produces several to monolayers.


Conclusion: 

Plasmonic-based nanosensors have received considerable attention due to their extraordinary sensitivity even at the single molecule level.  However, at present, plasmonic-enhanced nanosensors have not achieved excellent performances in practical applications, and their detection at femtomolar or atmolar concentrations is very challenging.

Researcher  and author: Dr.   (   Afshin Rashid)

Specialized doctorate in nano-microelectronics