_ Department of Nano Bioelectrical Laboratory (Nano Biosensors)

Nano-biosensors and nano-biochips in moving nano-particle molecules through dielectric enhancement through vertical nano-gap architectures 

Researcher  and author: Dr.   (   Afshin Rashid)



Note: The dynamic process of sorting and precise positioning of nanoparticle biomass in pre-defined microstructures is very important, however, this is a major obstacle to the realization of surface-sensitive nanobiosensors and practical nanobiochips.
A scalable, widespread and non-destructive trapping method based on dielectric forces is much needed for nanoparticle collection and nanobiosensing tools.  Here, we present a vertical nanogap architecture with an electrode-insulator-electrode stack structure.  Facilitate the generation of strong dielectric forces at low voltages, for precise capture and manipulation of nanoparticles and molecular assemblies, including lipid vesicles and amyloid-beta fibrillar proteins/oligomers.  Our vertical nanoplastic platform allows low-voltage nanoparticles recorded in optical dimensional designs, providing new opportunities for the fabrication of advanced surface-sensitive sensors.

Nano biosensors appear as a powerful alternative to conventional analytical techniques, as nanosensors perform highly sensitive, real-time, and high-frequency monitoring of pollutants without extensive sample preparation.  Nano biosensors can be integrated into small devices for rapid screening and monitoring of a wide range of pollutants. Since the nano biosensor  is an analytical device, used to detect a chemical substance, which  is a combination of a biological component with a physicochemical detector.  A sensitive biological element  , eg tissue, micro-organisms  , etc., a component of a material or biomimetic that interacts with and binds to nanoparticles.


A biosensor typically consists of a bioreceptor (enzyme/antibody/cell/nucleic acid/aptamer), a transducer component (semiconductor material/nanomaterial) and an electronic system  that includes a signal amplifier  , processor and screen. It is a show.  Transducers and electronics can be   combined,  for example, in CMOS-based microsensor systems . The detection component, often called a biological receptor, uses biomolecules from living organisms or organisms modeled after biological systems to interact with the analyte of interest.  This interaction is measured by the transmitter transmitter, which gives a measurable signal proportional to the presence of the target analyte in the sample.

Conclusion : 

In , the dynamic process of sorting and accurate positioning of nanoparticle biomasses in predefined microstructures is very important, however, this is a major obstacle to the realization of surface-sensitive nanobiosensors and practical nanobiochips.

Researcher  and author: Dr.   (   Afshin Rashid)

Specialized doctorate in nano-microelectronics