Programmable properties of nucleic acids in the development of nano-shaped and logically designed nano-machines (PhD in Nano-Microelectronics)
Researcher and author: Dr. ( Afshin Rashid)
Note: The programmable test properties of nucleic acids in creating nanoforms and logic nanomachines designed for a variety of applications. For this reason, one of the most studied areas in the field of nanorobotics today includes DNA assembly, especially a method called DNA origami.
Nano-scale folding DNA origami is DNA to create unwanted two-dimensional and three-dimensional shapes at the nanoscale . The interaction between complementary base pairs makes DNA a useful building block through the design of base sequences. DNA is a well-known substance that is suitable for creating scaffolds that hold other molecules or for building structures on their own. It has found a number of applications of drug delivery systems for use as circuits in plasmonic devices. However, most programs remain in a conceptual or experimental phase.
Although DNA is the natural choice for building active structures in nanobots, DNA is origami . Not for nanorobotic applications, but due to the lack of structural and catalytic diversity, molecular walkers on origami and switches are also possible. Nanorobots made of origami DNA show computational capabilities and are a pre-programmed task inside a living organism. In the structure of the DNA nanobot that they created, an open DNA tube is made from a It has a hinge side and can be closed. The drug-laden DNA tube is closed by a DNA aptamer and configured to identify and search for disease-related proteins. When the nano-robot origami DNA origami They strike infected cells, separate the aptamers, and release the drug.
Conclusion :
The programmable test properties of nucleic acids and DNA origami in creating nanoforms and logic nanomachines designed for a variety of applications. That's why today one of the areas to study the Nanvrvbvtyk, including DNA assembly, especially a technique called DNA origami DNA origami is
Researcher and author: Dr. ( Afshin Rashid)
PhD in Nano-Microelectronics