Nano Protein chips (structure and function) based on PhD in nano-microelectronics

Researcher  and author: Dr.   (   Afshin Rashid)




Note: A  Nano Protein chips have been developed  that can detect proteins with extremely high sensitivity. To make protein chips, a nano-microfluidic network has been used that allows easy modeling of proteins followed by molecular cognition. Water-soluble CdTe / CdS fluorescent nuclear shell quantum dots, water-synthesized phase, with high quantum performance and high stability, are used as signaling probes. It is compatible with microfluidic methods that contain highly sensitive protein nanoparticles  for cancer biomarker methods.

Structure of  nano-chips, protein chips Protein Nano ( detect proteins and DNA of cells)  is a sensitive circuit architecture to provide a larger sensor is scalable and allows real-time tracking to provide a clinical diagnosis. They used a   sensor  1 in 1.2  cm  custom  sensor to sensor 300   micrometers, which contains an array of eight and eight  sensor  rotation valve is used. Each sensor has an area of ​​90 by 90   microns, which is made in series by combining parallel sets in the form of magnetic nano-sensor strips to be able to adjust the surface of the coating independently of the resistance with the maximum applicable voltage in the range of 0.5.  V to prevent breakage of the passive thin layer The sensor uses paramagnetic particles ranging from micro to nanoparticles to various biomolecules that can detect very specific proteins.


Nano Protein chips are used to track the activities as well as protein bindings and discover their function on a large scale. Its main advantage is that it can be used to track large numbers of proteins in parallel. This protein chip includes a surface for support such as microtiter plate or nut, nitrocellulose membrane, glass slide. These are automatic, fast, economical, very sensitive, consume less samples.   

Conclusion : 

A  Nano Protein chips have been developed  that can detect proteins with extremely high sensitivity. To make protein chips, a nano-microfluidic network has been used that allows easy modeling of proteins followed by molecular cognition. Water-soluble fluorescent CdTe / CdS nuclear shell quantum dots, water-synthesized phase with high quantum performance and high stability, are used as signaling probes. It is compatible with microfluidic methods that contain  highly sensitive protein nanoparticles  for cancer biomarker methods.

Researcher  and author: Dr.   (   Afshin Rashid)

PhD in Nano-Microelectronics