🔬 Biological _ Electrical Nanosensors Section
The essential role of nanostructures in architecture (nanosensors and nanobiosensors)
Researcher and Author: Dr. ( Afshin Rashid)
Note: Many types of nanosensors have been designed using nanostructures for nanobiological applications. (Conductive surface) The oxidation of conductive polymer nanostructures is easily modified by redox mechanisms, and the charge transport properties of these nanostructures are also affected by structural parameters, such as diameter and dimensions.
Nanostructures are capable of providing sensitive and rapid responses to specific biological and chemical species. Techniques such as chemical polymerization are often used to create nanostructures .
Fabrication strategies can be divided into three categories: hard template synthesis, soft template synthesis, and template-free synthesis. The most widely used conductive polymers used in nanobiosensors, nanodevices made from nanostructures are used in various nanobiosensors due to their unique chemical and electrical properties resulting from the properties of their pi-electron nanosystems.
How to functionalize nanostructures to make nanobiosensors
Many patterning and functionalization technologies are being developed to control the location, distribution, amount, or structure and orientation of biomolecules on the surface of nanostructures . Therefore, the interface between biomolecules and nanostructures is of particular importance in numerous applications. Covalent and non-covalent modifications are two general methods for coupling biological molecules and nanostructures . Covalent functionalization is a chemical process in which a strong bond is formed between nanostructures and biomolecules or their relationship. In many cases, chemical surface modifications are necessary to create active groups that can bind to biomolecules. In contrast to covalent functionalization, in non-covalent methods, biomolecules are formed on the surface of nanostructures without destroying the geometric and electronic structure . Non-covalent interactions are of particular importance in many biological systems.
Conclusion:
The large surface-to-volume ratio of nanostructures and the high potential for signal amplification provide ideal conditions for labeling and detecting biological elements in nanobiosensor structures.
Researcher and Author: Dr. ( Afshin Rashid)
Specialized PhD in Nano-Microelectronics