🔬 Biological _ Electrical Nanosensors Section
Review of Nano Bio_Electronic Nanosensors; CDSE Nanosensor
Researcher and Author: Dr. ( Afshin Rashid)
Note: The creation of nanosensors based on nanoelectronics has also undergone a huge transformation in medical and biological research, and the technology of making biosensors and the knowledge of nanometric production of these devices has expanded day by day. These sensors are called (optical sensors) due to the use of optical fiber in their structure and are divided into two categories: chemical and biological.
In the manufacture of medical and biological nanosensors (biosensor), depending on whether we want to use this sensor to analyze intracellular species, intercellular biological fluid or blood, the dimensions of the sensor tip, the taper angle of its tip and the degree of softness of the coating on the fiber will vary. To prepare this fiber as a sensor tip, we can use devices used to stretch optical fibers. In this device, a carbon dioxide laser is used to heat the fiber and a device is used to stretch the fiber in the direction of its main axis. By changing the temperature and the amount of tensile force applied to the fiber, researchers have succeeded in making tips for biosensors that have a diameter between 0.1 and 511 nanometers. This technique has a high speed (about 3 seconds) and a relatively simple production process. This type of sensor was named (nanobiosensor) due to its nanometer size and its application in biological environments. Nanobiosensors are very small electrodes in nanometer size and cellular dimensions that have been made sensitive to the detection of desired chemical or biological species in cells by immobilizing specific enzymes on their surface .
These sensors are used to detect and quantify species in biological systems. This technique is a very useful method for detecting the passage of some molecules through the cell wall or membrane. The most famous example of nanosensors used in medicine is cadmium selenide (CdSe). This compound works to detect cancerous tumors using its fluorescence properties. The probe of the sensors made in this way can be inserted into the cell membrane without damaging it and can be used for biomolecular and clinical studies. In general, a biosensor assembly consists of a biological receptor molecule such as DNA or antibody that is placed on a very thin fiber. This assembly can be used as a probe to introduce a specific species into the cell and analyze the species inside the cell using conventional amperometric methods.
Conclusion:
The creation of nanosensors based on nanoelectronics has also undergone a huge transformation in medical and biological research, and the technology of making biosensors and the knowledge of nanometric production of these devices have been expanding day by day. These sensors are called (optical sensors) due to the use of optical fiber in their structure and are divided into two categories: chemical and biological.
Researcher and Author: Dr. ( Afshin Rashid)
Specialized PhD in Nano-Microelectronics