Performance and structure of bio chip nano in Lab on biological diagnostic chips (based on PhD in nano-microelectronics)
Researcher and author : Dr.Afshin Rashid
Note: Gene and protein microarrays in very small sizes with the ability to make molecular detections based on DNA and human protein sequences and other pathogens used for research.
Reproduction and Expansion of Nanochips The more specialized function of nanochips or gene and protein microarrays containing markers against the entire human genome is to study genetic variation. With the proliferation of nanochips and Lab on a chip microelements, medical diagnostic laboratories are able to study and measure hundreds of biological substances from blood cell counts to detailed examination of blood factors and other body fluids and tissues, clinical pathology laboratories Imaging systems such as radiology , ultrasound, endoscopy, CT scan, MRI and other specialized diagnostic methods for the examination of various diseases such as angiography, echocardiography, ECG and other organs are highly developed. . With the development of human knowledge in the fields of cellular and molecular sciences, genetics and identification of genes causing various diseases, determining the genome order of pathogens, reviewing and comparing them and creating genomic databases, developing molecular detection methods, specialized laboratories of this method Are used to accurately diagnose infectious pathogens, some genetic disorders, and even in some cases for prenatal diagnoses and the possibility of the fetus developing severe inherited diseases and determining the sex of the fetus.
(Microarray technology) Technology Microarray Gene and protein arrays Although several years have passed since the identification of the structure and determination of the complete sequence of the human genome and it has been determined that the human genome is composed of 3 billion new clotides and about 30,000 genes, but a major change in Inheritance diseases have not been solved and the causes of various human diseases have not been discovered due to the complexities in the human genetic structure and various factors affecting it. Because previously it was thought that a gene is responsible for an activity and experts studied the structure and function of individual genes and proteins separately, but now it has been determined that several genes are involved in some disorders and a number of processes in A disease or cellular or tissue damage is involved. The result is that a method must be devised to simultaneously examine the sequence, diversity, genetic differences, structure, and activity of tens, hundreds, and thousands of genes of proteins simultaneously.
The structure of carbon nanotubes good candidates for improving the sensitivity of the function and structure of the nano-bio-chip diagnostic bio chip nano in Biological Lab on chip ) , in the development of biological chips. These methods are part of the acquisition Information process in which information about the nature and structure of the bio chip nano in the laboratory on biological diagnostic chips in the environment is provided instantly. In this process, an amplified electrical signal is generated as a result of the presence and interaction of a nano-biological particle with a sensing layer. Therefore, the function and structure of bio chip nano in Lab on biological diagnostic chips include two main and key steps, which are detection and amplification. By the process described above is responsible for the function and structure of the nano-bio-chip bio chip nano in Lab on chip for biological detection is called the System Bio - Nano chip (Nano biochip system) in laboratory miniature that can They can perform hundreds or thousands of simultaneous biochemical reactions. Function and structure of nano-bio-chips Bio-chip nano in Laboratory Biological diagnostic chips quickly display a large number of biological analytes for a variety of purposes, from disease diagnosis to the detection of digital microfluidic biosypes in many biomedical fields to one They have become one of the most promising technologies. In the performance and structure of biochip nano In the Laboratory of Biological Diagnostic Chips , a group of (adjacent) cells in a microphilic array can be configured for storage, functional operation, and for the dynamic transfer of fluid droplets.
Conclusion:
Gene and protein microarrays in very small sizes with the ability to make molecular detections based on DNA and human protein sequences and other pathogens used for research.
Author: Dr. Afshin Rashid