_ Nanobiosensing tools section in (Nanoelectric)

Specific range ( nanobiosensing devices)  and dynamic performance in nanobiosensor structure

Researcher  and Author: Dr.   (   Afshin Rashid)


Note: One of the potential advantages of nanobiosensors over conventional sensors is their high sensitivity. The intrinsic sensitivity of a sensor is defined as the ratio of the sensor output signal to the change in sensor properties due to the amount of analyte bound to the sensor. This parameter can be considered as the ability of the sensor to convert an input signal into an output signal. 

A sensor with high sensitivity is capable of rapid instantaneous changes. Sensitivity can also be defined as a sensitivity test method, which describes how well a diagnostic test is able to detect a specific sample containing or without an analyte. Sensitivity in sensors affects some properties, such as repeatability and diagnostic accuracy.

Dynamic range in nanobiosensors

Another parameter that is rarely discussed in the context of nanobiosensors is the dynamic range of the sensor. This is the range in which the sensor is able to produce an output signal that is representative of the amount of analyte. The sensor response curve is linear and describes a wide range of analyte amounts and the corresponding sensor output  .

Dedicated functionality in nanobiosensors

In addition to being able to produce an output signal indicating the presence of an analyte, a sensor must be able to identify a specific analyte. This ability is called specificity and is the factor by which the sensor can be effective in an unobserved environment containing large amounts of unknown substances. Unlike sensitivity, measuring the specificity of a nanobiosensor  is difficult because the number of substances that should not produce an output signal is very large. Specificity is most useful when a sensor must  detect a small concentration of a specific analyte in an environment containing large amounts of non-target substances, many of which may bind non-specifically to the sensor and thus  produce an unusual signal.

Conclusion:

Gold nanoparticles have the ability to rapidly and directly transfer  electrons between a wide range of electroactive materials  . They also have light scattering properties and the ability to increase  the local magnetic field.  Gold nanobiosensors can be classified into three categories: optical nanobiosensors,  electrochemical nanobiosensors, and piezoelectric nanobiosensors  Metallic nanoparticles such as platinum and silver are also of great interest due to  their unique size and optoelectronic properties  . Their size depends on the optical, magnetic,  chemical, and electrical properties.

Researcher  and Author: Dr.   (   Afshin Rashid)

Specialized PhD in Nano-Microelectronics