Knowledge of (DNA Origami) and its use in the fabrication and replication of nanobiobots (biological nanobots) based on PhD in nano-microelectronics
Researcher and author: Dr. ( Afshin Rashid)
Note: "Origami" is a Japanese word that means folding a simple sheet to a desired shape and with a special dimension. DNA origami is one of the newest techniques of using DNA as building blocks in the synthesis of nano-robots Biologic nanoparticles (Nano bio Robot s) is . This is one of the newest methods in the field of nanoelectronics technology, which has its own limitations and opportunities.
Nano-scale folding DNA origami is DNA to create unwanted two-dimensional and three-dimensional shapes at the nanoscale . The interaction between complementary base pairs makes DNA a useful building block through the design of base sequences. DNA is a well-known substance that is suitable for creating scaffolds that hold other molecules or for building structures on their own. Has found a number of applications of drug delivery systems for use as circuits in plasmonic devices. However, most programs remain in a conceptual or experimental phase.
Although DNA is the natural choice for building the active structures of nanobots, DNA is origami . Not for nanorobotic applications, but due to the lack of structural and catalytic diversity, molecular walkers on origami and switches are also possible. Nano robots made from DNA origami DNA origami capacity computing to showcase the work of pre-programmed within the living organism. In the structure of nano-robots they have created DNA, a DNA pipes open a It has a hinge side and can be closed. The drug-laden DNA tube is closed by a DNA aptamer and configured to identify and search for disease-related proteins. When the nano-robot origami DNA origami They strike infected cells, separate the aptamers, and release the drug.
Origami DNA has a completely different approach to multi-strand design. Usually the genomic DNA of a circular single-stranded nucleotide Nano Bots (Nano bio Robot as a scaffold used and hundreds of short auxiliary called the punch for the latest Scaffolding longer specific structure is used. In the process of folding, DNA scaffolds Acts as a guide or a seed, which increases the folding efficiency and resistance to the stoichiometry of the filaments in the Nano bio Robot .
Conclusion:
Nano-scale folding DNA origami is DNA to create unwanted two-dimensional and three-dimensional shapes at the nanoscale . The interaction between complementary base pairs makes DNA a useful building block through the design of base sequences. DNA is a well-known substance that is suitable for creating scaffolds that hold other molecules or for building structures on their own. It has found a number of applications of drug delivery systems for use as circuits in plasmonic devices. However, most programs remain in a conceptual or experimental phase.
Author: Dr. ( Afshin Rashid)